Molecular targets of natural compounds with anti-cancer properties

M Kubczak, A Szustka, M Rogalińska - International Journal of Molecular …, 2021 - mdpi.com
… that curcumin might affect cancer cells by the modulation of … The diversities in cell signal
transduction caused by graviola … Studies were performed on human colorectal cancer cells (ex …

[HTML][HTML] Targeting cancer signaling pathways by natural products: Exploring promising anti-cancer agents

S Hashem, TA Ali, S Akhtar, S Nisar, G Sageena… - Biomedicine & …, 2022 - Elsevier
… by modulating the cancer microenvironment and different … - (JAK-) signal transducer and
activator of transcription factor … proliferation and colony formation in colon cancer cells, effects

Dietary phytochemicals in cancer signalling pathways: Role of miRNA targeting

A Shoaib, M Tabish, S Ali, A Arafah… - Current Medicinal …, 2021 - ingentaconnect.com
… in colon cancer cell via JAK2/STAT3 signalling pathway. The … in the modulation of miRNAs
as anti-cancer agents either by … deregulated via abnormal expression of signal transducer and …

MicroRNAs and natural compounds mediated regulation of TGF signaling in prostate cancer

Z Javed, K Khan, A Rasheed, H Sadia… - Frontiers in …, 2021 - frontiersin.org
… , and EMT in PCa via modulating the expression of TGF-β/AkT/… miRNA-23a-3p triggers
growth arrest and apoptosis in PCa … treatment reported to cause reduction in signal transduction

[HTML][HTML] Two Worlds Colliding: The Interplay Between Natural Compounds and Non-Coding Transcripts in Cancer Therapy

AA Sabo, M Dudau, GL Constantin, TC Pop… - Frontiers in …, 2021 - frontiersin.org
… limitation of introducing new anti-cancer natural products is lack … several natural compounds
may function via modulating the … both in vitro and in vivo (colon cancer xenografts in treated …

[HTML][HTML] Targeting miRNAs by natural products: A new way for cancer therapy

B Zhang, L Tian, J Xie, G Chen, F Wang - Biomedicine & Pharmacotherapy, 2020 - Elsevier
… better understand how natural products modulate miRNAs and … The anti-cancer activity of
curcumin and its analogues was … , glioma, prostate cancer, colon cancer, and neuroblastoma […

[HTML][HTML] Diterpenoid anthraquinones as chemopreventive agents altered microRNA and transcriptome expressions in cancer cells

YS Su, MZ Kuo, YT Kuo, SW Huang, CJ Lee… - Biomedicine & …, 2021 - Elsevier
… regulates the signal transduction pathways via microRNA (miRNA) … anti-cancer effect in lung
cancer cells and hepatocellular … line, HepG2, and human colorectal cancer cell line, HT-29. …

Chinese herbal medicines for prevention and treatment of colorectal cancer: from molecular mechanisms to potential clinical applications

M Kong, L Li, Y Lou, H Chi, J Wu - Journal of integrative medicine, 2020 - Elsevier
… their bioactive compounds for the prevention and treatment of … through modulation of cell
apoptosis and the cell cycle [5]. … diffusa (EEHDW) significantly inhibited the signal transducer

Anticancer natural medicines: An overview of cell signaling and other targets of anticancer phytochemicals

MF Akhtar, A Saleem, A Rasul, MMFA Baig… - European Journal of …, 2020 - Elsevier
… Janus-activated kinase/Signal transducer and activator of … Susceptibility of cancer cells
to anti-cancer drugs is decided … also induced apoptosis in human colon cancer cell (HT-29) …

Roles of plant‐derived bioactive compounds and related microRNAs in cancer therapy

H Zou, Y Li, X Liu, Z Wu, J Li, Z Ma - Phytotherapy Research, 2021 - Wiley Online Library
… So far, studies on the anti-cancer effects of bioactive compounds … -29 colon cancer (COAD)
cells by reducing the expression of … possibly through interleukin 6 (IL6)/signal transducer and …